Genetic and Epigenetic Marks Weave Intricate Connections in Cardiac Disease

Genetic and Epigenetic Marks Weave Intricate Connections in Cardiac Disease

With the new era of genome sequencing, the possibility to obtain affordable comprehensive DNA sequencing of a given human being can be foreseen in a relatively near future. Although the sequencing by itself is not any more a challenging technical problem, the relevance of the sequence to the phenotype, especially in terms of medicine, remains a complex conundrum, and specific approaches are pro...

Genetic and Epigenetic Marks Weave Intricate Connections in Cardiac Disease.

With the new era of genome sequencing, the possibility to obtain affordable comprehensive DNA sequencing of a given human being can be foreseen in a relatively near future. Although the sequencing by itself is not any more a challenging technical problem, the relevance of the sequence to the phenotype, especially in terms of medicine, remains a complex conundrum, and specific approaches are pro...

P-234: Altered Epigenetic Marks on Chromatin Condensing Genes of Sperm in TESE Negative Men Referred to Royan Institute

Onm-19: Role of Epigenetic in Transgenerarional Disease

Epigenetic alterations have been related to many biological processes and disease; however, the global epigenetic status of most cell types has not been investigated yet in detail. The ability of environmental factors to promote a phenotype or disease state not only in the individual exposed but also in subsequent progeny for successive generations is termed transgenerational inheritance. The m...

O-31: Epigenetic Aberration of HOXA10 Gene in Human Endometrium throughout The Menstrual Cycle in Endometriosis

Background: Epigenetic aberration such as DNA methylation and histone modifications appear to be involved in various diseases such as Endometriosis. Here, we investigated the epigenetic regulation of HOXA10 promoter, as a crucial gene, responsible for uterine organogenesis, functional endometrial differentiation and endometrial receptivity, and its correlation with mRNA expression of this gene ...